Venezia Santa Lucia is a terminal railway station serving the city of Venice, Italy. It is also the only (heavy rail) railway station in the historic city of Venice. The station is one of Venice's two most important railway stations, the other one being Venezia Mestre. Venezia Santa Lucia is located in Cannaregio, the northernmost of the six historic districts of the historic city, near the western end of the Grand Canal.
A bridge over the Grand Canal, the Ponte degli Scalzi links the concourse in front of the station with the sestiere of Santa Croce. Since 2008, the concourse has also been linked with Piazzale Roma, the car terminal in the historic city and main terminus for all bus routes in and out of Venice, and by another Grand Canal bridge, the controversial Ponte della Costituzione.
Construction of the Santa Lucia station began in 1860. In order to make room for both the station and its forecourt, a convent and the Church of Santa Lucia were demolished in 1861. The station, in turn, took up the name of the church. The current station building is one of the few modernist buildings facing the Grand Canal. It is the result of a series of plans started up by the rationalist architect Angiolo Mazzoni in 1924 and developed by him over the next decade. In 1934, a contest for a detailed design for the current station was won by Virgilio Vallot. Between 1936 and 1943, Mazzoni and Vallot collaborated on the construction of the station building, whereas Mazzoni also designed the train hall. This work, however, was completed only some years later, in 1952, on a design developed by another architect, Paul Perilli.
In November 2009, work began on the renovation of the station. The renovation programme would include improvements to the use of spaces and the flow of internal transit.