Villa Monzeglio was designed by an Italian immigrant Architect, Antonio Montini, in the capital of Venezuela, Caracas.

The building was cutting edge for its time, using concrete cantilevers and retaining walls, allowing the building to jut out over a steep, sloping hill and 'fly' off the hillside. It was intended to display an Italian-style of architecture in the Venezuelan capital.

It is alleged that the architect was commissioned to design Villa Monzeglio for a local Italian couple who ran a successful delicatessen. Senor Monzeglio wanted to give his wife a grand home.

On July 22 2005 it was declared by the Institute of Cultural Heritage as a Nation's Cultural Asset and is currently used for administrative purposes.